Platelet Recovery Formula:
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Platelet recovery measures the effectiveness of platelet transfusion by calculating the percentage increase in platelet count relative to the dose administered. It helps assess transfusion response and platelet viability.
The calculator uses the platelet recovery formula:
Where:
Explanation: This formula calculates the percentage increase in platelet count per unit of platelet dose administered, providing a standardized measure of transfusion effectiveness.
Details: Platelet recovery calculation is essential for evaluating transfusion efficacy, detecting platelet refractoriness, guiding transfusion therapy, and monitoring patient response to platelet transfusions.
Tips: Enter post-transfusion platelet count, pre-transfusion platelet count, and platelet dose. All values must be valid (counts ≥ 0, dose > 0). The result shows the recovery percentage.
Q1: What is considered a good platelet recovery?
A: Typically, a recovery >20% at 1 hour or >10% at 24 hours post-transfusion is considered adequate, though this may vary by institution and patient condition.
Q2: Why might platelet recovery be low?
A: Low recovery can indicate immune-mediated destruction (e.g., HLA antibodies), non-immune consumption (e.g., fever, infection, DIC), splenomegaly, or platelet product issues.
Q3: How is platelet dose measured?
A: Platelet dose is typically expressed in platelets × 10¹¹ per unit, though the exact measurement may vary by blood bank and product type.
Q4: When should platelet recovery be measured?
A: Recovery is typically measured 1 hour post-transfusion for immediate response assessment, and sometimes at 24 hours for platelet survival evaluation.
Q5: Are there limitations to this calculation?
A: This calculation assumes linear kinetics and doesn't account for factors like platelet sequestration, consumption, or individual variations in platelet distribution and survival.